You may remember my wails of complaint a couple of weeks back about my tablet PC and the Manga Studio 4 ink blobs. I had the opportunity to try out a clean install of Windows Vista and it happened there too.
I did manage to make it stop though. If you switch Manga Studio to "Wintab" mode in the preferences from "Tablet PC", you don't get the 1 in 100 strokes that loses pressure sensitivity (though you can enjoy a great simulation of how you would draw if you were steaming drunk). I think it's a Wacom Penabled driver problem linked just to this one application. In any case, since this isn't the machine I draw the comic on (you may remember my ancient two-ton second-hand Cintiq) I will wail no more.
I would however feel a lot less mad if one other person on the internet reported having this problem. The problem being, apparently, a ludicrous executive toy for a computer and a nice piece of software the authors let you (me) have for free.
More digital art yarns later in the week!